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乳酸激活训练免疫的机制及意义:三羧酸循环与组蛋白乳酸化的关键 ...
为探究环境营养可用性对训练免疫(trained immunity)的影响,研究人员开展了关于生理碳源(PCSs)对训练单核细胞葡萄糖利用影响的研究。结果发现乳酸是训练免疫的关键燃料,通过调节三羧酸循环(TCA cycle)和组蛋白乳酸化发挥作用,为理解先天免疫记忆提供 ...
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