Airway smooth muscle (ASM) plays a central role in the control of airway calibre and the pathogenesis of obstructive lung diseases. ASM cells surround the bronchial tree and respond to neural, ...

The contractile function of smooth muscle relies on the dynamic interplay of three principal cytoskeletal networks: actin filaments, intermediate filaments and microtubules. Actin polymerisation and ...

Using whole genome sequencing, researchers identified a single variant in a microRNA gene, MIR145-5p, as the source of multisystemic smooth muscle dysfunction syndrome, which had gone undiagnosed in a ...

Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed. Their findings, published in ...

Alpha smooth muscle actin (αSMA) fibroblast self-organization and interaction with the implant Upon biomaterial implantation, the team gained insights to the organization of alpha smooth muscle actin ...

RUDN University scientists have discovered that in weightlessness, the contractile activity of smooth muscles in the hollow organs of the gastrointestinal tract is disrupted. New data must be taken ...

Coronary artery disease is one of the most common forms of heart disease and a major cause of death. It develops when fatty ...

Scientists have discovered new clues about why cells that normally protect our arteries can sometimes change and help heart ...