The transforming growth factor-β (TGFβ) family are a large group of pleiotropic cytokines that function as extracellular ligands to induce downstream signalling pathways. Both the ligands and ...

Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients alike.

Wnt signalling has long been regarded to always activate the same groups of genes, leading to the term "Wnt target genes." But the current study upends this assumption, as the research group, led by ...