GLP-1 weight-loss drugs alter brain circuits in the amygdala and dopamine system to reduce the motivation to seek out high-calorie foods.

The drugs were found to engage a separate circuit linking the hindbrain to the central amygdala (emotions processing centre) ...

The concept of dopamine fasting has surged in popularity, particularly in high-performance environments like Silicon Valley. Proponents claim that temporarily abstaining from pleasurable activities ...