When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury. But in neurological disorders such as ALS and spinal muscular atrophy, or following spinal ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

Agriculture is fundamental to ensuring humanity’s food and fibre security. Synthetic pesticides pose challenges due to resistance, emissions, toxicity, and harm to beneficial organisms. A novel ...

Inactive Cas13 orthologs have been fused to a mutant human ADAR2 deaminase domain at the C terminus to enable programmable adenosine-to-inosine (A-to-I) RNA editing in selected transcripts. Although ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects. They can suppress infection by eliminating viral RNA, such as in ...

-- Novel approach to gene knockdown uses proprietary CASi (Conditionally Activated siRNA) molecules optimized to “switch” on, activating siRNA therapeutics only in selected cells -- -- CASi platform, ...

< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

Inside Philadelphia’s new RNA manufacturing hub, scientists are working to create vaccines for fish, precision pesticides and treatments to protect plants from extreme heat. The recently launched ...

DURING THE covid-19 pandemic new vaccines were rolled out with unprecedented speed. The fastest to arrive were jabs built from molecules of messenger RNA (mRNA) designed to teach the body how to fight ...

Scientists created a programmable RNA repair tool that selectively replaces harmful RNA regions while preserving healthy ...

TriLink’s CleanCap technology produces optimal 5′ cap structures with over 95% efficiency, creating a co-transcriptional capping solution that dramatically improves mRNA yield and process time when ...