Non-coding RNA is a ribonucleic acid molecule that is generated from the non-protein coding DNA sequence, that makes up 98-99% of the human genome. A plethora of different types of functional ...

Regulatory mechanisms mediated by non-coding RNAs provide valuable insights into the pathogenesis of idiopathic pulmonary fibrosis.

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

A new review article highlights the powerful influence of long non-coding RNAs (lncRNAs) in regulating natural killer (NK) cells, revealing promising opportunities to enhance immune responses and ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer cell invasion, tumor microenvironment shaping, ...

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

Association of tumor-informed minimal residual disease (MRD) with clinical outcomes for muscle invasive bladder cancer (MIBC): A multicenter retrospective real-world analysis.

“There is strong debate in the scientific community on whether the thousands of long non-coding RNAs generated from our genomes are functional or simply byproducts of a noisy transcriptional machinery ...

As a PhD student at the University of Münster in the early 2000s, Sven Diederichs would bike three kilometers each morning to a compact lab in a brick building on the hospital campus. There, he’d ...