An early burst of GPR3 activity helps convert short-term cellular signals into long-term programs that support neuron growth, ...

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.

Leuven, 7 August 2024—The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU ...

Cells have surface receptors that couple with proteins and other molecules to initiate or inhibit certain behaviors. Typically, the number of these receptors increases as the cell matures, but ...

The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

Dopaminergic neurons arise from progenitor cells in the ventral midbrain under the coordinated influence of morphogens such as Sonic Hedgehog, Wnt and FGF, and the action of transcription factors ...

A new study in zebrafish reveals that the gene nexmifb—a paralog of the human neurodevelopmental gene NEXMIF—plays a critical role in spinal motor neuron development by modulating the axon guidance ...

Dopamine is a catecholamine neurotransmitter that plays important roles in neuromodulation, such as motor control, motivation, reward, cognitive function, maternal behavior, and reproductive behavior ...

The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

Subscribe to our newsletter for the latest sci-tech news updates. The researchers also identified a second progenitor cell type that supports dopaminergic neuron development and survival. Dopaminergic ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...