阿尔茨海默病（AD）的进展被认为与疾病相关小胶质细胞（DAM）有关，但受限于技术，我们一直难以在人体组织中精准刻画它们的特征，以及它们与周围病理环境（如Aβ斑块）的真实互动。近期，《Nature ...

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life. Scientists have reasoned that replacing the ...

From everyday actions like walking and talking to feats of athletic or academic excellence, the brain is constantly acquiring and seamlessly processing information to produce these incredible ...

Summary: A collaborative neurobiology study uncovered a cellular mechanism tied to the severe, rapid progression of multiple sclerosis (MS). Published by a multidisciplinary team analyzing human ...

New study shows that microglia cells 'listen in' to neighboring neurons and change to match them. From everyday actions like walking and talking to feats of athletic or academic excellence, the brain ...

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development. By incorporating ...

Microglia are known to be important to brain function. The immune cells have been found to protect the brain from injury and infection and are critical during brain development, helping circuits wire ...

Researchers have identified that microglia first help spread Alzheimer’s disease pathology across the brain and then activate to limit its neurodegenerative effects. Researchers from the VIB-KU Leuven ...

One of the biggest controversies in neuroscience dates back to 1906, when Camillo Golgi and Santiago Ramón y Cajal argued their opposing views on brain structure. 1 Golgi hypothesized that brain cells ...