Kupffer cell adaptation in fibrotic liver disease. In healthy livers, KCs reside in sinusoids and rapidly capture blood-borne pathogens. In liver fibrosis, sinusoids are rarefied, leading to ...

This infographic summarizes key aspects of the proposed methodology for producing liver organoids. The liver organoids developed in this study aid in improving hemophilia A by secreting the essential ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...