Centralspindlin is a heterotetrameric protein complex consisting of dimeric kinesin-6 (Pavarotti or Pav-KLP in Drosophila melanogaster (Pav/kinesin-6), ZEN-4 in Caenorhabditis elegans and CHO1/MKLP1 ...

Zachary Gergely, Michele Jones, Bojun Zhou, Cai Cash, J. Richard McIntosh, and Meredith D. Betterton (2023). Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone ...

Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?

Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI: 10.1091/mbc.E15-07-0505. Download.

Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This process is especially important in neurons, which have highly polarized ...

Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping neurons healthy: ...

HOUSTON - (Jan. 28, 2021) - Like a wrench that gums up the gears, a common anesthetic keeps the motor proteins in your cells from making their rounds. This is not necessarily a bad thing, but how it ...

Researchers have found a new function for one of the proteins involved with chromosome segregation during cell division. A group of Dartmouth researchers has found a new function for one of the ...

Inside cells, microtubules not only serve as a component of the cytoskeleton (cell skeleton) but also play a role in intracellular transport. In intracellular transport, microtubules act as rails for ...