In May 1983, Kary Mullis, a young technician working for the Cetus Corporation, sat with idle hands and a busy mind. The laboratory he worked in was attempting to study DNA mutations linked to sickle ...

Nearly 40 years ago, American biochemist Kary Mullis developed the polymerase chain reaction (PCR). This technique impacted research in the life sciences so fundamentally that in 1993, less than a ...

In the summer of 1984, Henry Erlich, Glenn Horn, Randy Saiki, and myself were working on developing a DNA test for sickle cell anemia (SCA) at Cetus Corp. SCA is an autosomal dominant disease caused ...

Molecular biologists have always faced the challenge of working with the smallest of specimens, expending a great deal of time and energy attempting to manipulate substances millions of times smaller ...

I think all molecular biologists would recognize that the papers describing di-deoxy sequencing 1 and Kary Mullis' PCR technique 2 have changed the world of science profoundly. Mullis, a true "gonzo" ...