The prostate highly depends on androgens for its growth, development and functioning. Castration therapies aim at blocking signaling through the androgen receptor (AR), cause atrophy and epithelium ...

Insulin-like growth factors (IGFs) are peptide hormones that are primarily involved in stimulating the growth of many types of cells. They participate in the growth and function of almost every organ ...

A research team found a novel function of fibroblast growth factor 2 (FGF2), a self-renewal factor for spermatogonial stem cell (SSC) which is the origin of the sperm production. Although it has ...