The patent system is designed so that inventors who bear the burden of innovation risks and are successful in their efforts have the potential to reap substantial rewards. From a constitutional ...

Most advanced cancers are treated with drug combinations. Rational design aims to identify synergistic combinations, but existing synergy metrics apply to preclinical, not clinical data. Here we ...

After previously discussing permutations, Dr. James McCaffrey of Microsoft Research uses step-by-step examples and full code presentations to explore combinations. A ...

Combination therapy is essentially a one-two punch at cancer—sometimes with multiple punches. For people with lung cancer, it means treating a tumor with more than one type of therapy at the same time ...

Experts from industry and the U.S. Food and Drug Administration (FDA) recently joined forces to take a closer look at the interface of medical device and drug development, called combination products.

Many regulatory considerations may be unfamiliar to manufacturers pursuing market approval of combination products. Understanding and planning for these considerations can significantly affect FDA ...