In the standard corticotropin-stimulation test, which is used to assess the function of the hypothalamo–pituitary–adrenal axis, synthetic corticotropin is administered at a dose of 250 µg. Previous ...

In this study, we tested whether a test dose of i.v. BU at 0.8 mg/kg infused in adult patients 2 weeks before a myeloablative allogeneic HSCT would allow us to target a BU AUC of 4800 (range 4000–6000 ...

Many oral drugs show a high variability in pharmacokinetic exposure, and, for drugs with exposure related to efficacy, therapeutic drug monitoring can help optimize exposure in individual patients.

Factors predicting favorable outcome following autologous stem cell transplantation for primary refractory or relapsed Hodgkin’s disease: A prognostic model based on 20 year follow up ...

Johnson & Johnson is confident that it has a one-dose knockout vaccine that can protect against COVID-19, but it’s now starting a late-stage two-dose test just in case. The Big Pharma’s vaccine, ...

Results from a retrospective cohort study demonstrated the safety of an antimicrobial stewardship intervention that uses guideline-directed beta-lactam antibiotic test-dose procedures in hospitalized ...

A dexamethasone suppression test is primarily used to help diagnose Cushing syndrome. Cushing syndrome indicates that you have an abnormally high level of cortisol. Cortisol is a steroid hormone ...

What Is a Cortisol Test? A cortisol test measures the level of cortisol in your blood, urine or saliva. Cortisol is a hormone that's important throughout the body for maintaining blood pressure, blood ...

Is This the Right Drug for Me? Doc, what can you tell me about pharmacogenetics? If you pose that question to your physician, you want to find out whether a medication you're taking (or are about to ...