Vijay K. Kuchroo, PhD, DVM, of the Gene Lay Institute of Immunology and Inflammationof Brigham and Women’s Hospital, Massachusetts General Hospital and Harvard Medical School and the Ann Romney Center ...

Cytotoxic T lymphocytes play a crucial role in adaptive immunity, primarily defending against tumors and viruses. These cells develop within the thymus gland and undergo rapid activation upon ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ...

Scientists mapped the gene regulatory networks responsible for progressive differentiation states of tumor-infiltrating T cells, using a technology known as single-cell CRISPR screening to knock out ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

(L to R) Co-first authors Peipei Zhou, Ph.D., Hao Shi, Ph.D. and corresponding author Hongbo Chi, Ph.D., all of the St. Jude Department of Immunology. T cells are used in adoptive cell therapy (ACT) ...

In the Introduction to the Derivative video we introduce the notion of the derivative of a function and explain how the derivative captures the instantaneous rate of change of a function. In the ...