RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Next-generation sequencing is essential for microbiome research, as it enables comprehensive analysis of large datasets. Therefore, the robustness and accuracy of bioinformatic workflows for sequence ...

The eukaryotic/vertebrate genetic variance information was also obtainable from DNA recovered from the air. The hybridization-based target enrichment can capture genetic variant information from ...

ctDNA test, which is an important aspect in liquid biopsy, offers a non-invasive alternative to tissue biopsies for cancer diagnosis and monitoring. Ultra-deep ctDNA sequencing enabling the detection ...

Deep-sea researchers uncovered more than 500 million unique genes and a promising protein that could improve DNA sequencing technology.