Single-Molecule Localization Microscopy (SMLM) has traditionally faced challenges to optimize signal-to-noise ratio, penetration depth, field-of-view (FOV), and spatial resolution simultaneously. Here ...

The glycocalyx around the cell membrane is a pivotal structure in cell physiology. This layer consists of polysaccharides and sugars bound to either proteins (glycoproteins) or lipids (glycolipids).

Scientists have been peeking through microscopes and taking pictures of cells for decades. The methods available for visualizing highly complex cells have changed over time, moving from simpler ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Cell painting has established itself as a powerful tool for high content imaging, able to generate vast quantities of data in response to chemical perturbations. Over the past decade, cell painting ...

Pharmaron’s advanced high-content screening platform uses multiplexed fluorescent dyes to expose several organelles within cells. The subsequent image processing step extracts detailed morphological ...