Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...

Twice-yearly mass distribution of azithromycin to children is a promising intervention to reduce childhood mortality in sub-Saharan Africa. The World Health Organization recommended restricting ...

The Stepped Wedge Cluster Randomized Trial is a research methodology that has been growing in popularity, particularly for pragmatic implementation and dissemination trials. SW-CRTs can have ...

A Hybrid Type III Effectiveness-Implementation Trial to Optimize Medication Safety With Oral Antitumor Therapy in Real-World: The AMBORA Competence and Consultation Center We performed cluster random ...

In an open-label, two-period, two-sequence, cross-sectional, cluster-randomized, crossover trial, we assigned hospitals in Ontario, Canada, to use either lactated Ringer’s solution or normal saline ...