A case-control study is a type of medical research investigation often used to help determine the cause of a disease, particularly when investigating a disease outbreak or rare condition. If public ...

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...

We examine several tests of homogeneity of the odds ratio in the analysis of 2 x 2 tables arising from epidemiologic 1:R matched case-control studies. The T 4 and T 5 statistics proposed by Liang and ...

This is a preview. Log in through your library . Abstract We consider the problem of maximum-likelihood estimation in case-control studies of gene-environment associations with disease when genetic ...