Gene regulation in our cells—the decision on which proteins are produced for the various processes of the cell—is strictly regulated. It has long been assumed that this regulation deteriorates with ...

We quantified age-related changes in gene regulatory relationships across eight human tissues. Our results reveal that the gene–gene relationships that become stronger with age affect mostly genes ...

Investigation of transcriptomic signatures of aging has uncovered alterations in several processes, either as possible causes of cellular damage or as adaptive responses to age-related functional ...